解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:Balanced adjustment of the portal vein shunt volume during a transjugular intrahepatic portosystemic shunt (TIPS) is critical for maintaining liver perfusion and decreasing the incidence of liver insufficiency. A stent-graft is proved to be superior to a bare metal stent (BMS) for the construction of a TIPS....
journal_title:Chinese medical journal
pub_type: 杂志文章,随机对照试验
doi:10.4103/0366-6999.182830
更新日期:2016-06-05 00:00:00
abstract:BACKGROUND:Oxygen inhalation therapy is essential for the treatment of patients with chronic mountain sickness (CMS), but the efficacy of oxygen inhalation for populations at high risk of CMS remains unknown. This research investigated whether oxygen inhalation therapy benefits populations at high risk of CMS. METHODS...
journal_title:Chinese medical journal
pub_type: 杂志文章,随机对照试验
doi:10.4103/0366-6999.182831
更新日期:2016-06-05 00:00:00
abstract:BACKGROUND:Survivin is an oncoprotein silenced in normal mature tissues but reactivated in serous ovarian cancer (SOC). Although transcriptional activation is assumed for its overexpression, the long 3'-untranslated region (3'-UTR) in survivin gene, which contains many alternate polyadenylation (APA) sites, implies a p...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.181965
更新日期:2016-05-20 00:00:00
abstract:BACKGROUND:Acute fatty liver of pregnancy (AFLP) is a rare but life-threatening complication occurring in the third trimester. It is often fatal to both mother and fetus. The complicated clinical manifestations as well as an insufficient understanding of the disease make the precise diagnosis and effective treatment of...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.181963
更新日期:2016-05-20 00:00:00
abstract:BACKGROUND:Proteasome subunits (PSMB) and transporter associated with antigen processing (TAP) loci are located in the human leukocyte antigen (HLA) Class II region play important roles in immune response and protein degradation in neurodegenerative diseases. This study aimed to explore the association between single n...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.180513
更新日期:2016-05-05 00:00:00
abstract:BACKGROUND:While combined oral contraceptives (COCs) are commonly used to treat polycystic ovary syndrome (PCOS), comparative data regarding metabolic effects of different progestogens on this patient population are missing. This study aimed to compare the different effects of drospirenone (DRP)-containing COCs with cy...
journal_title:Chinese medical journal
pub_type: 杂志文章,随机对照试验
doi:10.4103/0366-6999.179783
更新日期:2016-04-20 00:00:00
abstract:BACKGROUND:The prevalence of sudden sensorineural hearing loss in children (CSSNHL) is consistently increasing. However, the pathology and prognosis of CSSNHL are still poorly understood. This retrospective study evaluated clinical characteristics and possible associated factors of CSSNHL. METHODS:One hundred and thir...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.179791
更新日期:2016-04-20 00:00:00
abstract:BACKGROUND:Menopausal symptoms and sleep difficulty were physiological processes that were affected by genetic and other factors. This study was to investigate the prevalence of menopausal symptoms and sleep quality in menopausal transition (MT) and postmenopause (PM) women in Taiyuan, Shanxi. METHODS:A community-base...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.178961
更新日期:2016-04-05 00:00:00
abstract:BACKGROUND:The interaction between activated microglia and T lymphocytes can yield abundant pro-inflammatory cytokines. Our previous study proved that thymus immune tolerance could alleviate the inflammatory response. This study aimed to investigate whether intrathymic injection of myelin basic protein (MBP) in mice co...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.178955
更新日期:2016-04-05 00:00:00
abstract:BACKGROUND:Wolf-Hirschhorn syndrome (WHS) is a contiguous gene syndrome that is typically caused by a deletion of the distal portion of the short arm of chromosome 4. However, there are few reports about the features of Chinese WHS patients. This study aimed to characterize the clinical and molecular cytogenetic featur...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.177996
更新日期:2016-03-20 00:00:00
abstract:BACKGROUND:The treatment for long bone defects has been a hot topic in the field of regenerative medicine. This study aimed to evaluate the therapeutic effects of calcium sulfate (CS) combined with platelet-rich plasma (PRP) on long bone defect restoration. METHODS:A radial bone defect model was constructed through an...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.176981
更新日期:2016-03-05 00:00:00
abstract:BACKGROUND:The conventional method cannot guarantee the precise osteotomies required for a perfect realignment and a better prognosis after total knee arthroplasty (TKA). This study investigated a customized guide plate for osteotomy placement in TKAs with the aid of the statistical shape model technique using weight-b...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.176082
更新日期:2016-02-20 00:00:00
abstract:OBJECTIVE:5-Fluorouracil (5-FU)-based combination therapies are standard treatments for gastrointestinal cancer, where the modulation of autophagy is becoming increasingly important in offering effective treatment for patients in clinical practice. This review focuses on the role of autophagy in 5-FU-induced tumor supp...
journal_title:Chinese medical journal
pub_type: 杂志文章,评审
doi:10.4103/0366-6999.176069
更新日期:2016-02-20 00:00:00
abstract:BACKGROUND:Total hip arthroplasty (THA) in developmental dysplasia of the hip (DDH) is more complex than the normal hip, with large replacement risks and many complications. Although nonosteotomy THA is convenient to perform, femoral osteotomy shortening can avoid blood vessel and nerve traction injuries. This study ai...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.174507
更新日期:2016-02-05 00:00:00
abstract:BACKGROUND:Smoking and body mass index (BMI) are the key risk factors for chronic obstructive pulmonary disease (COPD). Adiponectin with both anti-inflammatory and pro-inflammatory properties is a vital modulator of inflammatory processes, which is expressed in epithelial cells in the airway in COPD-emphysema. The aim ...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.173486
更新日期:2016-01-20 00:00:00
abstract:BACKGROUND:The dyschromatoses are a group of disorders characterized by simultaneous hyperpigmented macules together with hypopigmented macules. Dyschromatosis universalis hereditaria (DUH) and dyschromatosis symmetrica hereditaria are two major types. While clinical and histological presentations are similar in these ...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.172564
更新日期:2016-01-05 00:00:00
abstract:BACKGROUND:Previous studies suggested that zinc level was related to a certain diabetic microvascular complication. However, the relationship between zinc level and all the microvascular complications in type 2 diabetic patients remains unknown. The purpose of this study was to analyze the relationship between zinc lev...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.171357
更新日期:2015-12-20 00:00:00
abstract:BACKGROUND:There are more than 300 genetic loci that have been found to be related to hereditary hearing impairment (HHI), including 92 causative genes for nonsyndromic hearing loss, among which 34 genes are related to autosomal dominant nonsyndromic HHI (ADNSHHI). Traditional linkage analysis and candidate gene sequen...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.171440
更新日期:2015-12-20 00:00:00
abstract:BACKGROUND:Hamstring (HS) autograft and bone-patellar tendon-bone allograft are the most common choice for reconstruction of anterior cruciate ligament (ACL). There was a little report about the clinical outcome and difference of arthroscopic ACL reconstruction using allograft and autograft. This study aimed to compare...
journal_title:Chinese medical journal
pub_type: 杂志文章,随机对照试验
doi:10.4103/0366-6999.170265
更新日期:2015-12-05 00:00:00
abstract:OBJECTIVE:To introduce the imaging characteristics of moyamoya disease (MMD) using high-resolution magnetic resonance imaging (HR-MRI) and to discuss the role of HR-MRI in differentiating MMD from other intracranial artery diseases, especially intracranial atherosclerotic disease (ICAD). DATA SOURCES:This review was b...
journal_title:Chinese medical journal
pub_type: 杂志文章,评审
doi:10.4103/0366-6999.170257
更新日期:2015-12-05 00:00:00
abstract:BACKGROUND:It is important to choose an appropriate antiepileptic drug (AED) to manage partial epilepsy. Traditional AEDs, such as carbamazepine (CBZ) and valproate (VPA), have been proven to have good therapeutic effects. However, in recent years, a variety of new AEDs have increasingly been used as first-line treatme...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.168968
更新日期:2015-11-20 00:00:00
abstract:BACKGROUND:Na + /Ca 2+ exchanger (NCX) plays a crucial role in pentylenetetrazol-induced convulsion. However, it is unclear whether NCX is critically involved in hyperthermia-induced convulsion. In this study, we examined the potential changes in NCX3 in the hippocampus and cerebrocortex of rats with hyperthermia-induc...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.169103
更新日期:2015-11-20 00:00:00
abstract:BACKGROUND:To avoid the irritation of tendons and soft tissues as well as hardware-related problems, we designed an intramedullary fixation with bioabsorbable rods for the treatment of the metacarpal shaft fractures. METHODS:Five patients with nine shaft fractures of the fourth and fifth metacarpi were treated with in...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.168040
更新日期:2015-11-05 00:00:00
abstract:BACKGROUND:Adenoid hypertrophy (AH) is associated with pediatric chronic rhinosinusitis (pCRS), but its role in the inflammatory process of pCRS is unclear. It is thought that innate immunity gene expression is disrupted in the epithelium of patients with chronic rhinosinusitis (CRS), including antimicrobial peptides a...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.168056
更新日期:2015-11-05 00:00:00
abstract:BACKGROUND:With the progress of perinatal medicine and neonatal technology, more and more extremely low birth weight (ELBW) survived all over the world. This study was designed to investigate the short-term outcomes of ELBW infants during their Neonatal Intensive Care Unit (NICU) stay in the mainland of China. METHODS...
journal_title:Chinese medical journal
pub_type: 杂志文章,多中心研究
doi:10.4103/0366-6999.167312
更新日期:2015-10-20 00:00:00
abstract:OBJECTIVE:This review aimed to summarize the relationship between intestinal microbiota metabolism and cardiovascular disease (CVD) and to propose a novel CVD therapeutic target. DATA SOURCES:This study was based on data obtained from PubMed and EMBASE up to June 30, 2015. Articles were selected using the following se...
journal_title:Chinese medical journal
pub_type: 杂志文章,评审
doi:10.4103/0366-6999.167362
更新日期:2015-10-20 00:00:00
abstract:BACKGROUND:Premature ventricular contractions (PVCs) are common in the general population, and frequent PVCs may result in the poor quality of life or even the damage of cardiac function. We examined the efficacy and safety of a traditional Chinese medicine Wenxin Keli for the treatment of frequent PVCs among a relativ...
journal_title:Chinese medical journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.4103/0366-6999.166026
更新日期:2015-10-05 00:00:00
abstract:BACKGROUND:The molecular mechanisms underlying the endometriosis are still not completely understood. In order to test the hypothesis that the approaches in phosphoproteomics might contribute to the identification of key biomarkers to assess disease pathogenesis and drug targets, we carried out a phosphoproteomics anal...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.166022
更新日期:2015-10-05 00:00:00
abstract:BACKGROUND:Long-term use of benzalkonium chloride (BAC)-preserved drugs is often associated with ocular surface toxicity. Ocular surface symptoms had a substantial impact on the glaucoma patients' quality of life and compliance. This study aimed to investigate the effects of sodium hyaluronate (SH) on ocular surface to...
journal_title:Chinese medical journal
pub_type: 临床试验,杂志文章
doi:10.4103/0366-6999.164927
更新日期:2015-09-20 00:00:00
abstract:BACKGROUND:This study was to examine the expression of total vascular endothelial growth factor (VEGF) and the anti-angiogenic VEGF 165 b isoform in the vitreous body of retinopathy of prematurity (ROP) patients, and to further study the role of the VEGF splicing in the development of ROP. METHODS:This was a prospecti...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.164937
更新日期:2015-09-20 00:00:00
abstract:BACKGROUND:Intravascular ultrasound (IVUS) examination can provide useful information during endovascular stent graft repair. However, its actual clinical utility in thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (type B-AD) remains unclear, especially in complicated aortic dissection. We eval...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.163386
更新日期:2015-09-05 00:00:00
abstract:OBJECTIVE:Intermediate-risk acute myeloid leukemia (IR-AML), which accounts for a substantial number of AML cases, is highly heterogeneous. We systematically summarize the latest research progress on the significance of gene mutations for prognostic stratification of IR-AML. DATA SOURCES:We conducted a systemic search...
journal_title:Chinese medical journal
pub_type: 杂志文章,评审
doi:10.4103/0366-6999.163400
更新日期:2015-09-05 00:00:00
abstract:BACKGROUND:The SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery Score II (SS-II) can well predict 4-year mortality in patients with complex coronary artery disease (CAD), and guide decision-making between coronary artery bypass graft surgery and percutaneous coronary intervention (PCI)....
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.162510
更新日期:2015-08-20 00:00:00
abstract:OBJECTIVE:To focus on the asthmatic pathogenesis and clinical manifestations related to epithelial sodium channel (ENaC)/chlorine ion channel. DATA SOURCES:The data analyzed in this review were the English articles from 1980 to 2015 from journal databases, primarily PubMed and Google Scholar. The terms used in the lit...
journal_title:Chinese medical journal
pub_type: 杂志文章,评审
doi:10.4103/0366-6999.162494
更新日期:2015-08-20 00:00:00
abstract:BACKGROUND:Limited data exist on the association of serum gamma-glutamyl transferase (GGT) level within the reference range with the increased risk of coronary heart disease (CHD) prediction in men. The study examined the association between serum GGT concentration within the reference range and the CHD risk prediction...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.161343
更新日期:2015-08-05 00:00:00
abstract:BACKGROUND:The postremission therapies for adult patients generally contain consolidation chemotherapy, allogeneic hematopoietic stem cell transplantation and autologous hematopoietic stem cell transplantation (auto-HSCT). Because of the various results from different centers, the optimal therapy for adult acute lympho...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.161365
更新日期:2015-08-05 00:00:00
abstract:BACKGROUND:Although the early clinical outcomes of total knee arthroplasty (TKA) using minimally invasive surgery techniques have been widely described, data on the mid- to long-term outcomes are limited. We designed a retrospective study to compare the two most common TKA techniques - The modified quadriceps-sparing (...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.160521
更新日期:2015-07-20 00:00:00
abstract:OBJECTIVE:To review the origin, diagnosis, treatment and public health concern of New Delhi metallo-β-lactamase (NDM)-producing bacteria. DATA SOURCES:We searched database for studies published in English. The database of PubMed from 2007 to 2015 was used to conduct a search using the keyword term "NDM and Acinetobact...
journal_title:Chinese medical journal
pub_type: 杂志文章,评审
doi:10.4103/0366-6999.160566
更新日期:2015-07-20 00:00:00
abstract:BACKGROUND:To study the characters of high-frequency oscillations (HFOs) in the seizure onset zones (SOZ) and the nonseizure onset zones (NSOZ) in the electrocorticography (ECoG) of patients with neocortical epilepsy. METHODS:Only patients with neocortical epilepsy who were seizure-free after surgery as determined wit...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.159342
更新日期:2015-07-05 00:00:00
abstract:BACKGROUND:During the last 3 decades, China has dramatic changes of the dietary pattern among its citizens, particularly in urban cities. This study aimed to determine the nutrient intake status and factors associated with nutrient intakes of urban Chinese pregnant women now-a-day. METHODS:The multistage stratified ra...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.159354
更新日期:2015-07-05 00:00:00